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Times critiques Libya’s deadly nonsense

October 14th, 2006


Editorial rejects political fantasy blaming Bulgarians for HIV positive babies

Sets itself a good example with brief appearance of scientific reasoning to save lives

The Libyan HIV∫AIDS insanity continues. The five Bulgarian nurses and Palestinian doctor are still seriously in danger of execution in Libya because they are held responsible for spreading HIV among hundreds of babies in the hospital they worked in.

The New York Times editorial board comes to their defense very strongly today (Sat Oct 14) in every way they know of, except of course the one basis that really makes the story worthy of being called a “medical-legal travesty” of reason and justice, which is that HIV is not in fact an instrument of death, contrary to the claims of a paradigm which is scotched in numberless ways in the literature including a number of recent mainstream papers which, as we have pointed out, remove the main pillars of the paradigm.

In other words, the main authorities of the belief in HIV∫AIDS themselves have quietly contradicted in mainstream scientific papers the platform they stand on, and if the New York Times editorial writer would continue applying his/her mind to the problem in Libya a little longer and widen his/her focus to the paradigm itself, the editorial position could be even more enlightened.

But the New York Times has no inkling of this, of course, and its defense of the Bulgarian nurses rests on the obvious falsity of the Libyan claims even according to the analysis of Luc Montagnier, who says that the infections emerged before the accused started working at the hospital and continued to spread after they were thrown in jail.

Needless to say the Times editorialist only has to do a little more reading of what “one of the world’s greatest experts on H.I.V., Dr. Luc Montagnier” has said about the topic of HIV∫AIDS to discover that the relatively civilized (relative to his Stateside confreres in HIV∫AIDS) Montagnier believes that HIV is not sufficient to cause AIDS anyway and that nutritional factors are crucial.

Maybe the editorial board should think some more about the situation and apply their new interest in science to the fundamental HIV∫AIDS belief they support in their news columns with the incessant refrain “HIV, the virus that causes AIDS”, as included in this very editorial.

Otherwise, when the world finally comes to its senses about this failed paradigm, which still has no genuine support in the literature after 22 years, they will find themselves partly responsible for these six deaths if God forbid they happen as well as innumerable other ones among AIDS patients who are given ARVs.

October 14, 2006

Editorial

A Medical-Legal Travesty in Libya

Five Bulgarian nurses and a Palestinian doctor are facing the death penalty in Libya based on preposterous charges that they deliberately infected hundreds of children with H.I.V., the virus that causes AIDS. This looming miscarriage of justice demands a strong warning to the Libyan leader, Muammar el-Qaddafi, that his efforts to join the ranks of peaceable nations will suffer if the medical workers are made the scapegoats for the failure of Libya’s own health system.

The doctor and nurses, who had been working at a hospital in Benghazi, were arrested in 1999. They confessed under torture, according to human rights organizations, but later protested their innocence. The charges that they deliberately infected more than 400 children were clearly bogus.

One of the world’s greatest experts on H.I.V., Dr. Luc Montagnier, testified that the real cause of the infections was poor hygienic practices at the hospital. The infections emerged before the accused started working at the hospital and continued to spread after they were thrown in jail.

It seems clear that the government wanted to deflect public outrage by accusing foreigners of committing a horrific crime — rather than acknowledging the negligence of Libya’s health system.

The six medical workers were convicted and sentenced to death in 2004, while nine Libyans who worked at the same hospital were acquitted. The convictions were overturned by the Libyan Supreme Court, which ordered a retrial. Defense attorneys fear the same outcome this time. The attorneys are calling for another independent scientific assessment of the case because the evidence offered by Dr. Montagnier and an Italian scientist was tossed out by the courts.

Thus far the United States and European nations have focused on setting up an international fund to care for victims of the tragedy and to upgrade equipment at the hospital — in hopes that will be enough to get the medical workers set free. Libya is demanding substantial compensation as well, analogous to what it paid to families of the victims of the 1988 bombing of Pan Am Flight 103.

That seems a grotesque overreach given that the nurses and doctors are the victims here. The White House holds Libya up as a model for other nations to follow in renouncing weapons of mass destruction. Libya must also be judged by how it respects human rights and the rule of law.

Tough stuff, right on the mark. When will they apply the same mind set to HIV∫AIDS itself?

Or is that too much to hope for, that the world’s greatest newspaper free itself of the shackles of censorship that Dr Anthony Fauci of NIAID has imposed on the media for 22 years?

Here is a Nature/Reuters report from 20 Sept:

Nature

Published online: 20 September 2006; | doi:10.1038/443254b

Lawyers call for science to clear AIDS nurses in Libya

International pressure needed to save health workers from death penalty.

Declan Butler

Lawyers defending six medical workers who risk execution by firing squad in Libya have called for the international scientific community to support a bid to prove the medics’ innocence. The six are charged with deliberately infecting more than 400 children with HIV at the al-Fateh Hospital in Benghazi in 1998, so far causing the deaths of at least 40 of them.

On 28 August, when the prosecution was scheduled to close its case, the Libyan prosecutor called for the five Bulgarian nurses and a Palestinian doctor to be sentenced to death. Attorneys from Lawyers Without Borders, who are handling the defence of the six, have responded by calling for the international community to request that the court order an independent scientific assessment, by international AIDS experts, of how the children became infected.

Five Bulgarian nurses and a Palestinian doctor stand accused of infecting hundreds of children with HIV.

L. LARBI/REUTERS

The medics were condemned to death in May 2004, but the Supreme Court quashed their convictions last December, following international protests that the first trial had been unfair. It ordered a retrial, which has run intermittently since 11 May at the Criminal Court of Benghazi, based in Tripoli. A verdict is expected within weeks.

But the scientific community has so far shown relatively little interest in the case, says Emmanuel Altit, a member of the Paris bar and a volunteer with Lawyers Without Borders, who has in the past defended inmates at Guantanamo Bay. “We have knocked on a lot of doors, but we have not had much help; we hope this will change.”

It’s scandalous. This is a complex affair, and it is impossible to judge it without a scientific basis.

One reason for the lack of interest, he says, is the widespread notion that the trial is a sideshow, and that the “real decisions” will be made by diplomats (see Libya’s travesty). Altit argues that diplomacy has so far failed to secure results, and that the medics’ release will only be secured by using scientific evidence to fight the case in the Tripoli courtroom. He hopes that exposing the “emptiness” of the prosecution case will ramp up enough international pressure to force governments to take action.

At present, the case has been sidelined by broader geopolitical interests in the opening of oil-rich Libya to international relations, says Antoine Alexiev, another defence lawyer on the case. The United States decided in May to re-establish diplomatic relations with Libya. And Muammar Gaddafi, the Libyan leader, has been given red-carpet treatment at the European Union’s headquarters in Brussels — without mention of the medics’ situation.

First report

During the first trial, the Libyan government did ask Luc Montagnier, whose group at the Pasteur Institute in Paris discovered HIV, and Vittorio Colizzi, an AIDS researcher at Rome’s Tor Vergata University, to examine the scientific evidence. The researchers carried out a genetic analysis of viruses from the infected children, and concluded that many of them were infected long before the medics set foot in Libya in March 1998. Many of the children were also infected with hepatitis B and C, suggesting that the infections were spread by poor hospital hygiene. The infections were caused by subtypes of A/G HIV-1 — a recombinant strain common in central and west Africa, known to be highly infectious.

But the court threw out the report, arguing that an investigation by Libyan doctors had reached the opposite conclusion. Montagnier believes the judgement was based at least partly on mistranslation from English to Arabic of the term ‘recombinant’ — instead of referring to natural recombination of wild viruses, as intended, it was interpreted to mean genetically modified, implying human manipulation.

According to Alexiev, the decision to throw out the report removed all scientific content from the case, leaving a series of prejudgements, and confessions extracted under torture. “It’s scandalous,” he says. “This is a complex scientific affair, and it is impossible to judge it without a scientific basis.”

Montagnier, whose efforts helped secure a retrial in the first place, says he too is upset by how events in Tripoli are progressing. “It’s a rerun of the first trial,” he says. “It’s embarassing politically for Gaddafi, but there is the pressure of the parents, who absolutely need to find a scapegoat. Of course this can’t be the Libyans, so it falls on the medics.”

The defence is scheduled to plead on 21 September, but Altit is not convinced that the science will be fairly heard. All attempts by the defence to present its arguments have been “systematically blocked”, he claims, for example by switching the schedule. “The trial should be fair and equitable; until now it has been anything but.”

Legally, the Montagnier/Colizzi report cannot be reinstated after having been thrown out, so the defence is pinning its hopes on persuading the court to appoint an independent science panel to produce a new report. The Tripoli court has resisted all such calls, says Alexiev. “We are hitting a wall, and that is unlikely to change before the end of this trial.”

The defence is therefore resigned to probably losing the current trial, he says, and is setting its sights on the six’s last chance: a final appeal in the Supreme Court, which could convene immediately after the Tripoli verdict, currently expected in November. “We need to convince the Supreme Court to nominate that international scientific assessment,” he says.

“If international pressure isn’t stronger before the appeal, the risk is large that they will be condemned to death,” predicts Michel Taube, co-founder of Together Against the Death Penalty, a French non-governmental organization. “To avoid that outcome, diplomacy is not enough. We need international mobilization.”

Only a combined pressure from lawyers and scientists as well as politicians will make a difference, agrees Altit. If the Supreme Court refuses a scientific assessment, then the international community will be able to ask: “What has it got to hide?” he says. “And if it agrees to a scientific investigation, then we will win.”

Buy a red Nano, save an African life

October 13th, 2006


Finally, eyeball proof that HAART works: Alicia visits Mombasa, with crew

Child dies on ARVs, after 14 years without ARVs. Why is Bono overlooked by the Nobel Committee?

Have the critics of HIV∫AIDS misled us? That’s what we are forced to ask after today’s Oprah Winfrey show, and NBC news, which was devoted to Bono and his new Red campaign to raise money for ARVs for needy Africans.

Not only did Oprah and Bono demonstrate that buying red versions of cool gear could save the lives of children with AIDS in Africa. But Alicia Keys reported finding out from her emotionally moving visit (with film crew) to Mombasa that some African children are not given ARVs for years after they are born with HIV, and may die as a result, even when they finally are given the drugs.

The clinic is dispensing ARVs to needy children now, however, courtesy of Oprah’s Angel network. But, we are shown, it may be too late. Sudi, one child photographed by her video crew as Alicia sat with his family trying to be encouraging, cried because he hadn’t had drugs until he was fourteen, though now he was getting them. You could see the tears running down his cheeks. Back in the studio, Oprah enquired after Sudi’s health, and Alicia with lowered voice confided that the poor child had “passed away” a week later. Well, it was a miracle that he had survived so long, Oprah pointed out, since he hadn’t been able to get the drugs until he was 14.

Having seen all this eyewitness testimony on screen with our own eyes we feel somewhat aggrieved. How could we have been taken in so easily by all the claims of HIV∫AIDS critics that HIV doesn’t cause AIDS, and that the drugs aren’t any good for you? They simply don’t fit what one sees on the screen.

Well, now they can’t keep on saying this, because Oprah, Alicia Keys and Bono have told us and 22 million other viewers how much better the Africans feel when they are discovered to be suffering from HIV and are given ARVs at last, courtesy of those who buy red gear, whereby a portion of the price goes to Bono’s Red movement to deliver ARVs to the needy.

“Now customers can buy the best music player in the world and do something to help the world at the same time,” said Steve Jobs, Apple’s CEO. “We’re honored to work with Bono, (RED) and this team to contribute to an incredibly important initiative and help change the way people think about AIDS in Africa.”

Several other companies are offering red-colored products in support of Bono’s charity. The Gap is selling several red-colored clothing items, and Motorola is offering a red-colored RAZR.

Apple Offers Red iPod to Fight AIDS

Apple Offers Red iPod to Fight AIDS

By Ed Oswald, BetaNews

October 13, 2006, 2:06 PM

Apple said Friday that it had teamed up with U2 front man Bono to offer a special edition of the iPod Nano. However, unlike the full-size iPod that was designed for the band, this music player supports Bono’s charity Red, which fights diseases in Africa, primarily AIDS.

The 4GB Nano is enclosed in a red case, and will sell for $199 USD. For each unit sold, Apple will donate $10 to the Global Fund to help fight HIV/AIDS in Africa. In addition, the iPod includes a special $25 Red iTunes Gift card, although it didn’t specify what percentage would go to charity.

“Now customers can buy the best music player in the world and do something to help the world at the same time,” said Steve Jobs, Apple’s CEO. “We’re honored to work with Bono, (RED) and this team to contribute to an incredibly important initiative and help change the way people think about AIDS in Africa.”

Several other companies are offering red-colored products in support of Bono’s charity. The Gap is selling several red-colored clothing items, and Motorola is offering a red-colored RAZR. While the some of the products have been available in the UK since April of this year, Friday marks the first day the products became available in the US.

“It’s wonderful to see this incredible level of commitment from companies that are willing to lend their creativity in the fight against AIDS in Africa, the greatest health crisis in 600 years,” Bono said in a statement.

Yes, readers, we are going to go out and buy a red Nano at once, or at least, as soon as we need one. For we saw with our own eyes Oprah Winfrey and Bono today showing us how if they buy a red $79.99 Motorola phone with two year contract, that will yield $17 for ARV medicine for those in need. Oprah scooped up ten, which meant $170, enough for ARVs for one African for one year. This was after she bagged ten red iPods, each of which meant $10 more drugs for Africans with HIV, and before she collected ten Armani red T shirts, and ten Armani Bono type wraparound sunglasses.

“This is so cool!” said Oprah. “Thank you Apple!” as she left the Apple store and with her arm round Bono’s shoulders continued on a Red item shopping tour of Chicago, with crowds of fans kept back behind ropes at the doorways of the stores, some of whom Oprah handed Armani sunglasses.

“That was so much fun!” she said.

Back in the studio, she welcomed Alicia King – “Don’t we all love her?!” – offering her a red T shirt. But Alicia turned it down, because she will buy a red T shirt herself to support the movement. She was just back as mentioned from visiting the family care clinic in Mombasa hospital. We see her visit on camera. She tells them she is so glad that they are feeling better on the medicines the Oprah Angels are able to provide.

On screen, Alicia sits with the HIV doomed family. One is Sudi, with tears running down his cheeks. Sudi hasn’t improved. He is the one that has had HIV since he was born, but only got medicines when he was 14, courtesy of Oprah’s Keep a child alive! network. But HIV has got him in its grip, regardless, and a week after Alicia’s encouraging visit, she reports, he died. But as Oprah notes cheerfully, it is amazing he stayed alive so long without treatment. Alicia agrees. She informs us that he would still be alive today if he had had ARVs when he was 3 years old.

“It is the simplest thing to save a life in Africa. It is so simple!” says Alicia.

Drugs have immediate effect

It wasn’t just Alicia, either, who told us how important and effective ARV drugs are in Africa. The woman in charge of the hospital gratefully described how the ARVs do good visibly and immediately to the chilren. “They start gaining weight, their height just shoots up astronomically, they have no fever, no infections, they no longer cough. A year later you can’t tell the difference between children with HIV and those without.”

How can HIV∫AIDS critics argue with that direct testimony?

Alicia reports that there are 25 million already dead from AIDS in Africa. “These children look at me and say if it wasn’t for you I wouldn’t be alive today.”

At this point, the basic facts having been established and a solution to the AIDS threat in Africa having been provided through shopping, it was time for the entertainment factor to be escalated, and so we were treated to Alicia Keys and Bono singing an unprecedented, never to be repeated duet: “Don’t give up Africa!”

Picture of a skeletal child…slogans appearing on the screen and melting away…”Don’t give up Kenya.”… “Don’t give up Uganda.”… “Don’t give up Zimbabwe.”… Don’t give up South Africa”…as the two mellifluous voices of the two superstars sigh, coo and squeak their way through the sentiment of the day… “It gonna be alright… Don’t give up, Please don’t give up. Whatever may come, whatever may go.. that river’s flowing… that river’s flowing. Don’t give up. There’s no reason to feel ashamed… Somewhere there’s a place. Africa…UHHHH FREEEEE KA AHAHAHAHAHAH….”

Bono’s launch of his Red campaign also won a mention on NBC news tonight. According to NBC announcer Brian Williams, the money “will help save the estimated 6500 Africans that die from AIDS every day.”

So where is the Nobel prize for AIDS?

The only people who seem to be insufficiently impressed so far are the Nobel Peace prize committee, who once again passed over Bono to celebrate a man who has brought a way of making a living to millions.

The lead singer of U2, born Paul Hewson in 1960, was among the favorites for the peace prize in the past two years. This year’s contenders also included former Finnish President Martti Ahtisaari and Indonesian President Susilo Bambang Yudhoyono.

“Over 60 percent of the money we took went on Bono, so it’s a bit of a disappointment for punters,” said Ken Robertson, a spokesman for the Dublin-based bookmaker Paddy Power Plc. “I’ve no doubt he’ll win it at some stage, perhaps when they need to re-energize it.”

Do the Nobel Peace Commitee know something we don’t? It’s not just Bono they haven’t favored, but where is the Nobel prize for Robert Gallo, once the most referenced scientist in the world, who first came up with the theory that HIV caused AIDS, and has stuck with that view through a pile up of contrary evidence over 22 years that would have defeated a lesser man?

Perhaps they are thinking of a combined Gallo Bono Peace prize, which would avoid getting into the embarrassing science of the matter.

But this would of course overlook the giant contribution of Anthony Fauci of NIAID in protecting the paradigm from nosy media reporters and others who might discover that it has not so far been proven in the scientific literature, which has on the other hand produced more reasons for rejecting it that you can shake a stick at.

Given that Anthony Fauci has pointed out that the solution to HIV∫AIDS may well be to add more HIV to stimulate the immune system (see previous post, NAR nominates Dr Anthony Fauci for Nobel – he has found the solution to AIDS), not to mention that HIV entry blocks the cell suicide of infected cells, and that antioxidants will stop HIV replication, perhaps he and Gallo, who first showed that HIV was not the cause of AIDS, and who has also shown antioxidants can protect the cells against cell suicide, can share a Nobel in Medicine for their contribution, now endorsed by the glamor and authority of Oprah Winfrey and Alicia Keys, as well as the renowned Bono.

Nobel Peace Prize Overlooks Rocker Bono for Bangladeshi Banker

Nobel Peace Prize Overlooks Rocker Bono for Bangladeshi Banker

By Sara Marley

Oct. 13 (Bloomberg) — As Muhammad Yunus of Bangladesh won the Nobel peace Prize at 5 a.m. New York time, the Irish rock star Bono announced the Red charity in the U.S., backed by Gap Inc., Converse Inc. and Viacom Inc.’s MTV Networks.

Motorola Inc. and Apple Inc. introduced Red-branded products in separate statements at the same time, with a portion of sales going to HIV and AIDS programs in Africa. Bono is appearing on the “Oprah Winfrey Show” today to promote the initiative.

The lead singer of U2, born Paul Hewson in 1960, was among the favorites for the peace prize in the past two years. This year’s contenders also included former Finnish President Martti Ahtisaari and Indonesian President Susilo Bambang Yudhoyono.

“Over 60 percent of the money we took went on Bono, so it’s a bit of a disappointment for punters,” said Ken Robertson, a spokesman for the Dublin-based bookmaker Paddy Power Plc. “I’ve no doubt he’ll win it at some stage, perhaps when they need to re-energize it.”

Last year’s peace prize went to the International Atomic Energy Agency and its Egyptian director general, Mohamed ElBaradei. Wangari Maathai, a Kenyan environmentalist, won in 2004.

Bono has been mentioned as a candidate for the peace prize since at least 2003, with the likes of Pope John Paul II, former Czech President Vaclav Havel and Ukrainian President Victor Yushchenko.

Geldof Too

Another Irish singer, Bob Geldof, 55, was nominated by a former member of Norway’s Parliament this year. He set up the 1985 Live Aid and 2005 Live 8 concerts to raise awareness and money in the fight against poverty. Australian bookmaker Centrebet gave each singer the same odds of winning, 33-1.

Bono wrote “Walk On” for 1991 Peace Prize winner Aung San Suu Kyi of Myanmar, according to the World Entertainment Network.

Motorola will start selling a red version of its Razr phone in the U.S., donating $17 per handset sold to Bono’s charity, Leslie Dance, a Motorola vice president, said in an interview on Oct. 11.

Apple announced a $199 Red special edition iPod nano with a $10 donation to Bono’s Global Fund for each sale.

Apple has teamed up before with U2, which won five Grammy awards this year with the album “How to Dismantle an Atomic Bomb.” The first black U2 iPod, with the band members’ autographs etched on the back, was introduced in November 2004.

To contact the reporter on this story: Sara Marley in London at smarley1@bloomberg.net .

Last Updated: October 13, 2006 09:55 EDT

Nobel for the Big Bang, not for Halton Arp

October 11th, 2006


Times fanfare for Mather and Smoot doesn’t mention fly in ointment of Big Bang

Arp’s redshift problem another paradigm flaw swept under carpet?

Dennis Overbye’s piece on the Big Bang Nobel in the Times last week (Wed Oct 4) was guaranteed to give inattentive Times readers a warm fuzzy feeling in its story of merit long recognized and now rewarded, a paradigm confirmed with yet another seal of approval, and universal agreement on a popular idea. But to heresy mavens who know to look for them, it was interesting also to see hints of lingering problems with the theory, even though a certain scientist wasn’t likely to be mentioned.

In fact, the success story of the Big Bang paradigm also contains familiar examples of the same politics of paradigm power seen at work in HIV∫AIDS – censorship of a highly respected scientist, ostracism and exile of the same for sticking to unpopular ideas, and the distorting effects of the politics of popularity and success.

COBE proves Big Bang with tiniest measurements

The story in the Times reported this year’s Nobel award to the two physicists who led 1,000 scientists, engineers and technicians who worked on the COBE (Cosmic Background Explorer) satellite launched in 1969. Their measurement of the microwave radiation in the universe thought to be left over from the Big Bang and the irregularities they found bolstered the Big Bang as the only theory which could account for the phenemona.

A result was a resounding confirmation of a universe born in a terrific explosion of space and time 14 billion years ago and in which the ordinary matter that makes up stars and people is overwhelmed by some mysterious “dark matter.”

“What we have found is evidence for the birth of the universe and its evolution,” Dr. Smoot said in a news conference on the results in 1992. About a map showing the splotchy seeds of galaxy formation, he famously said, “If you are religious, it is like looking at God.”

The work led to a wave of theorizing about the dark matter and dark energy that permeates the universe and pushes it apart in “what is known as a preposterous universe”, says Overbye, who doesn’t explain what he means by “preposterous”. Is the paradigm nicknamed ‘the preposterous paradigm’? If so, why?

The work “set cosmology in the track to our present well-based theory of the expanding universe,” according to James Peebles, a cosmologist at Princeton, and Michael Turner, a cosmologist at the University of Chicago, chimes in with the assertion that COBE and its measurements had heralded a “golden age” of “precision cosmology”.

A dream realized

COBE allowed precise measurements of the “lumps” in the distribution of the radiation which were hot and cold spots (we are talking of variations of a hundred thousandth of a degree here) which were so small that hopes of measuring them seemed like a “pipe dream”.

In April 1992, however, Dr. Smoot electrified a meeting of the American Physical Society in Washington by reporting that the COBE Differential Microwave Radiometer had seen and mapped the lumps.

Cosmologists now believe that these lumps or ripples are a result of quantum fluctuations, tiny jitters in the force fields that filled the universe when it was a fraction of a millionth of a second old.

A cosmologist at MIT, Max Tegmark, says the discovery of cosmic microwave fluctuations was as revolutionary for physics as the discovery of DNA was for biology. “These fluctuations are our cosmic DNA, the blueprints encoding how the baby universe would develop.”

Exciting stuff. These guys can measure fluctuations of a hundredth of a thousandth of a degree left over from the universe’s birth when it was a fraction of a millionth of a second old. Now they are getting the second Nobel seal of approval, following the 1978 award to Arno Penzias and Robert Wilson of Bell Labs, who first heard the cosmic background radiation as a persistent radio hiss in 1964.

That was when the Big Bang rose to unchallenged ascendancy in the paradigm wars in cosmology, Overbye writes, and

overnight, the few partisans of the rival steady-state theory of an unchanging universe melted away. But the only way to be sure was to measure the microwaves in all directions and at all wavelengths from space, away from atmospheric distortions and influences.

The tool for this task was COBE.

Forgive us in our ignorance if we say it seems to us that cosmology is getting almost as fanciful as nuclear physics in accounting for experimental results, and that it seems possible that refinements might be made in the Big Bang paradigm in the future, even if it is not toppled. “The COBE results provide increased support for the Big Bang scenario” wrote the Royal Swedish Academy of Sciences in citation, a small concession to those who might object that the theory has its skeptics still.

That pride in the paradigm may cometh before a fall, or anyway that in describing the universe things since COBE have become almost unbearably tangled again, see George Johnson’s piece in the Week In Review on Sunday:

If only it had been that simple. Six years after COBE, another Berkeley scientist, Saul Perlmutter, found something that almost no one had expected. By now, it was assumed, the universe should have settled down, expanding at a steady pace or even slowing, braked by its own gravity. Instead it appeared to be in overdrive, not ballooning as violently as it had in the inflationary era but expanding at a faster and faster rate. Something seemed to be pushing on the accelerator — what has come to be called dark energy, a mysterious kind of anti-gravity.

Shoehorning the new ingredient into the prevailing framework has created new Nobel-sized problems.

Oh, for the Simple Days of the Big Bang

The New York Times

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October 8, 2006

Oh, for the Simple Days of the Big Bang

By GEORGE JOHNSON

FOURTEEN years ago, when a Berkeley astronomer named George F. Smoot declared that he and his satellite, the Cosmic Background Explorer, or COBE, had detected the astrophysical equivalent of the fingerprints of God, his euphoria was easy to understand. For a few happy years, one of the last big pieces of the cosmological puzzle seemed to be in place — an explanation why the universe has blossomed into such an interesting place to live.

Had it not been for the whorls and dimples Dr. Smoot and his NASA collaborator, John C. Mather, found in the background radiation — the afterimage of the Big Bang — there would be no cosmic scenery. No galaxies or other vast conglomerations of matter, just a smooth expanse of visual nothing. Kansas instead of Colorado.

Subsequent discoveries have muddled the picture, so much so that last week’s announcement that the two men will share a Nobel Prize in physics was almost bittersweet — an occasion to celebrate a pivotal moment in science but also to look back with nostalgia on more innocent times.

The creation story supported by the data from the COBE satellite had seemed almost tantalizingly complete. Dr. Smoot’s smudges themselves weren’t sticky enough to gather particles into globs the size of the Milky Way or the Virgo supercluster. But if you spiked the Big Bang with an invisible additive called dark matter — a clumping factor — and hot-rodded the theory with a brief, early burst of rapid expansion called cosmological inflation, you could get the tiny irregularities in the background radiation to sprawl into something like today’s sky.

If only it had been that simple. Six years after COBE, another Berkeley scientist, Saul Perlmutter, found something that almost no one had expected. By now, it was assumed, the universe should have settled down, expanding at a steady pace or even slowing, braked by its own gravity. Instead it appeared to be in overdrive, not ballooning as violently as it had in the inflationary era but expanding at a faster and faster rate. Something seemed to be pushing on the accelerator — what has come to be called dark energy, a mysterious kind of anti-gravity.

Shoehorning the new ingredient into the prevailing framework has created new Nobel-sized problems. Basic physics predicts that if it exists at all, this repulsive force should be extremely large. Instead, the dark energy is infinitesimal and no one has been able to say why.

Except, that is, for followers of a controversial doctrine called the anthropic principle. There is no fundamental reason, they say, why the dark energy is so weak. It is just that if it were much stronger, space would have expanded too rapidly to harbor stars and, ultimately, life. The implication is that there is a multitude of possible universes, each with its own physics. Naturally, we are in one where it is possible for us to exist.

Depending on their temperament, physicists find the idea of a spectrum of universes each ruled by different laws either liberating or a source of despair. Since the days of the Greek philosophers, the reigning assumption, more mystical than scientific, has been that things are necessarily the way they are. There is one universe and lurking somewhere within is a deep principle that explains why the strength of gravity, the speed of light, the heft of matter — all the constants of nature — have taken certain values.

With Smoot and Mather, science seemed closer to finding the key — a hope that now sometimes seems as egotistical as the pre-Copernican belief that we live at the center of creation instead of on a hospitable rock orbiting an obscure star in an obscure galaxy in a universe that may be obscurer still.

More recently this faith in our own uniqueness has been tested again by a related finding in superstring theory, which began some 30 years ago as an attempt to pull all the numbers of the cosmos from a few basic calculations. Just as x + y + z = 42 has many solutions (infinitely many if you allow fractions or negative numbers), so do the equations of superstring theory. By one reckoning, the number of conceivable universes, each with a different dose of dark energy, is so vast that it is “measured not in the millions or billions but in googols or googolplexes.” (Before it was retooled into the name of a search engine, a googol was defined as 10 to the power of 100 and a googolplex as 10 to the power of googol.) Why we find ourselves in, say, universe number 110,310,077,252 would again be a tautology: if we weren’t we wouldn’t be here to ask. There may yet be a way out of the muddle with some insight that focuses superstrings into a beam illuminating the one true theory.

But new ideas, some physicists complain, are a dime a dozen. What they crave is new data, perhaps from the Large Hadron Collider scheduled to go online near Geneva next year. What is discovered there might do for physics what the COBE measurements did for cosmology in 1992: provide some long-needed reality testing.

If not there is always Plan B. Maybe physicists in another universe are coming closer to an answer.

Halton Arp, establishment heretic

We do know of one simple reason for saying that the Big Bang may not be entirely nailed down yet and that is the remarkable saga of Halton Arp, a protege of Edwin Hubble himself, who fell from grace with the US cosmological fraternity when he discovered a large number of huge anomalies which didn’t fit into the Big Bang very well. He was prevented from speaking to conferences here on the topic, and in the end was effectively exiled to the Max Planck Institute in Germany.

The red shift dilemma

Arp discovered a number of galaxies associated with quasar pairs where, according to the red shift, the quasars appeared to be receding very rapidly from us, while the galaxies appeared relatively close by, receding much more slowly. Yet the two entities were observed to be linked together. In other words, the red shift calculation on which the description of the shape and behavior of the universe is currently based cannot be correct after all. Something has to explain the “peculiar galaxies” which Arp has found, enough of them to fill a reference volume which finds a place on the shelves on leading astronomers.

This is how it is described at Arp’s site, which has A Short Biography of Halton C. Arp:

Halton C. Arp received his Bachelors degree from Harvard College in 1949 and his Ph.D. from California Institute of Technology in 1953, both cum laude. He is a professional astronomer who, earlier in his career, conducted Edwin Hubble’s nova search in M31. He has earned the Helen B.Warner prize, the Newcomb Cleveland award and the Alexander von Humboldt Senior Scientist Award. For 28 years he was staff astronomer at the Mt.Palomar and Mt. Wilson observatories. While there, he produced his well known catalog of “Peculiar Galaxies” that are disturbed or irregular in appearance.

Arp discovered, from photographs and spectra with the big telescopes, that many pairs of quasars (”quasi-stellar objects”) which have extremely high redshift z values (and are therefore thought to be receding from us very rapidly – and thus must be located at a great distance from us) are physically connected to galaxies that have low redshift and are known to be relatively close by. Because of Arp’s observations, the assumption that high red shift objects have to be very far away – on which the “Big Bang” theory and all of “accepted cosmology” is based – has to be fundamentally reexamined!

A more detailed discussion of the specific issue of “intrinsic redshift” and why Arp is said to be wrong is here at the Wiki: Intrinsic redshift

A scholar and a gentleman

Having met Halton Arp, at the 2001 Conference on Science and Democracy in Naple’s Institute for Philosophical Studies, perhaps the only conference in the world which gives respect and a platform to science’s otherwise damned heretics, we were surprised to hear how badly he was treated in the US for coming up with this difficulty, and for sticking with it. In manner and bearing he is clearly a gentleman and a scholar, and as his Wiki entry notes, his survey of galaxies is a solid reference.

His papers and observations are as sharp and combative as ever, as can be seen from his web site which carries them. For example, Astronomy By Press Release – News From A Black Hole

Accretion processes onto Black Holes are supposed to enable them to radiate high energy X-rays. When X-ray telescopes found strong X-ray sources in galaxies they said, aha, this is too strong to be an X-ray star so it must be a black hole in orbit around a star – a binary with a massive black hole revolving around it. Discovery of these now MASSIVE Black holes was so exciting that innumerable papers have appeared showing the X-ray positions and deep photographs at the positions the objects.

Strangely, when these objects were seen optically no one took spectra in order to see what they actually were. Finally a paper appeared in a refereed Journal where the authors showed the spectra of two of them to be that of high redshift quasars! Just to cement the case they looked at previously identified quasar in or close to galaxies and in 24 out of 24 cases the quasars belonged to the class of Ultra Luminous X-ray Sources.

This result is a double disaster in that the massive Black Holes turned out to be high redshift quasars, not a Black Hole in a binary star. Perhaps worse, they have been accepted as members of nearby galaxies and therefore cannot be out at the edge of the universe. Bye bye Big Bang and all that fundamental physics. (This result was not put out as a press release.)

The Halton Arp entry in the Wiki on Halton Arp describes all this in more technical detail, but doesn’t fully explain why the issue should be such a sore point. The standard line is that telescopes have been radically improved since Arp came up with his observations and accompanying theorizing which conflicted with the Big Bang, and that the galaxies which have high red shift are in fact very far away.

Since Arp originally proposed his theories in the 1960’s, however, telescopes and astronomical instrumentation have advanced greatly. QSO’s are now generally accepted to be very distant galaxies with high redshifts. Moreover, many objects that are high-redshift counterparts to normal nearby galaxies have been idenfitied in many imaging surveys, most notably the Hubble Deep Field[2]. Moreover, the spectra of the high-redshift galaxies, as seen from X-ray to radio wavelengths, match the spectra of nearby galaxies (particularly galaxies with high levels of star formation activity) when corrected for redshift effects. Very few astronomers today accept any of Arp’s hypotheses on QSO’s or galactic redshifts.

Notice the appeal to the popularity of an idea as a reason to have confidence in it, which is hardly proven by the history of HIV∫AIDS, and anyway is by definition a bad idea. Science is not a democracy where truth is decided by votes.

There is more to it, at least as far as Arp is concerned:

Nonetheless, Arp has not wavered from his standpoint against the Big Bang and still publishes articles stating his contrary view in both popular and scientific literature, frequently collaborating with Geoffrey Burbidge and Margaret Burbidge[3]

A film was made in 2004 about this by Randall Meyers, “The Cosmology Quest” released by Floating World Films. It has been shown in the US and many other countries in film festivals, to astronomy clubs and at conferences, and on Norwegian TV four times. The film shows that the steady state alternative is still alive and kicking with Arp and a few other holdouts, though there is no sign of it regaining momentum any time soon.

The reviews on Amazon of the DVD are here.

They suggest that there is still no satisfying explanation for the discrepancy, and that it is still possible to wonder who is right, and suspect that the complete lack of discussion might reflect the psychology of paradigm power more than can be intellectually justified.

The disgrace of science is the censorship

Certainly the censorship of Halton Arp’s ideas in the US seems no more justified than any other repression of free speech, particularly in science. As Jefferson wrote in 1779, one of this country’s founding principles is “that truth is great and will prevail if left to herself, that she is the proper and sufficient antagonist to error, and has nothing to fear from the conflict, unless by human interposition disarmed of her natural weapons, free argument and debate.”

In the world of cosmology it seems we have another instance of the unpleasant character of successful scientists, whose ideas become vessels for their pride, arrogance, ambition, envy and personal spite, instead of the professional objectivity which the naive suppose would be the rule, particularly in cosmology of all places.

The sad truth appears to be that the majority of professional scientists, like the majority of human beings, are much more powerfully ruled by the attractions of success than they are by the objective contemplation of truth.

Perhaps they should be reminded that it was Hitler who said that “success is the sole earthly judge of right and wrong,” and hold themselves to a higher standard.

We are of course referring to the realm of HIV∫AIDS as much as cosmology.

Two Americans Win Nobel in Physics

The New York Times

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October 4, 2006

2 Americans Win Nobel in Physics

By DENNIS OVERBYE

Two American astronomers who uncovered evidence on the origin of the universe and how it grew into galaxies were awarded the Nobel Prize in Physics on Tuesday.

The astronomers, John C. Mather of the NASA Goddard Space Flight Center in Greenbelt, Md., and George F. Smoot of the Lawrence Berkeley National Laboratory at the University of California, Berkeley, will split the prize of 10 million Swedish kroners, about $1.37 million.

Dr. Mather and Dr. Smoot led a team of more than 1,000 scientists, engineers and technicians behind the Cosmic Background Explorer, or COBE, satellite launched in 1989. Its mission was to study a haze of microwave radiation thought to be a remnant of the Big Bang that started the universe.

In its citation, the Royal Swedish Academy of Sciences wrote, “The COBE results provided increased support for the Big Bang scenario for the origin of the universe, as this is the only scenario that predicts the kind of cosmic microwave background radiation measured by COBE.”

The satellite measured the temperature and distribution of the microwaves, including the detection of faint irregularities, the seeds from which things like galaxies could have grown. A result was a resounding confirmation of a universe born in a terrific explosion of space and time 14 billion years ago and in which the ordinary matter that makes up stars and people is overwhelmed by some mysterious “dark matter.”

“What we have found is evidence for the birth of the universe and its evolution,” Dr. Smoot said in a news conference on the results in 1992. About a map showing the splotchy seeds of galaxy formation, he famously said, “If you are religious, it is like looking at God.”

The announcement of the prize delighted astronomers who had long anticipated a Nobel for the COBE work, which led to a wave of theorizing and experiments that have contributed to the emerging picture of what is known as a preposterous universe, full of dark energy pushing it apart as well as dark matter.

James E. Peebles, a Princeton cosmologist, said, “COBE was deeply important. Those two measurements set cosmology on the track to our present well-based theory of the expanding universe.”

Michael S. Turner, a cosmologist at the University of Chicago, said the COBE measurements had ushered in an era of “precision cosmology” that continues to this day. “This is likely to be the first of a number of prizes in cosmology in this golden age we find ourselves in,” Dr. Turner said.

This was not the first prize for work involving cosmic background radiation, which was discovered as a persistent radio hiss by Arno A. Penzias and Robert W. Wilson of Bell Laboratories in 1964. They received a Nobel in 1978. Measurements by them and a rapidly growing army of radio astronomers, including the late David T. Wilkinson of Princeton, suggested that the microwaves were uniform and fit the spectrum of a so-called black body with a temperature of about 3 degrees Kelvin above absolute zero, the signature of a dying Big Bang fireball when the cosmos was only 400,000 years old.

Overnight, the few partisans of the rival steady-state theory of an unchanging universe melted away. But the only way to be sure was to measure the microwaves in all directions and at all wavelengths from space, away from atmospheric distortions and influences.

The tool for this task was COBE.

Dr. Mather, who was born in 1946 in Roanoke, Va., and grew up near Rutgers University in rural New Jersey, studied at Swarthmore College and then at the University of California, Berkeley. He has worked for NASA his entire career.

He has been involved with the satellite since 1974, when it was first a gleam in NASA’s eye. Until then, he said at a news conference at NASA headquarters in Washington, he had been hoping to get out of the microwave work because it was too difficult. “But here I am,” he said.

Dr. Mather served as overall project scientist for the COBE mission and headed one of its three instrument teams, in an experiment to measure the spectrum of the microwaves precisely. Praising the COBE results as a “huge team effort,” he recalled that his perspective was that “this was a mission that was impossible.”

The satellite was launched in 1989, after a delay caused by the explosion of the space shuttle Challenger in 1986. The results from Dr. Mather’s instrument, the Far Infrared Absolute Spectrophotometer, or Firas, established that the Big Bang afterglow had a perfect black body spectrum with a temperature of 2.725 degrees Kelvin.

Dr. Smoot, who was born in 1945 in Yukon, Fla., and studied physics as an undergraduate and a graduate student at the Massachusetts Institute of Technology, was lead investigator for a COBE instrument designed to measure spatial variations in the microwaves.

Astronomers knew that the radiation could not be completely uniform because the universe today is not uniform. Matter is concentrated in galaxies. According to the standard theory, the seeds for these galaxies should show up as slight hot and cool spots in the relic of the Big Bang fireball. Many cosmologists, however, worried that these lumps, amounting to a hundredth of a thousandth of a degree, according to the best theories, were beyond detection.

Lawrence M. Krauss, a cosmologist at Case Western Reserve University, said, “People had hoped to see lumps, but it almost looked like a pipe dream.”

In April 1992, however, Dr. Smoot electrified a meeting of the American Physical Society in Washington by reporting that the COBE Differential Microwave Radiometer had seen and mapped the lumps.

Cosmologists now believe that these lumps or ripples are a result of quantum fluctuations, tiny jitters in the force fields that filled the universe when it was a fraction of a millionth of a second old.

Max Tegmark, a cosmologist at M.I.T., said: “I think the discovery of cosmic microwave fluctuations was as revolutionary for physics as the discovery of DNA was for biology. These fluctuations are our cosmic DNA, the blueprints encoding how the baby universe would develop.”

The seeds in COBE’s map correspond to superclusters of thousands of galaxies, the largest assemblages of matter in the modern universe. In discussing the results in the 1990’s, Dr. Smoot said that it was partly to emphasize the gigantic scale of these fluctuations, as well as their importance, that he had made the comment about seeing God.

He received a fair amount of ribbing in the news media for that comment. In an interview with The New York Times in 1992, he said, “It really is like finding the driving mechanism for the universe, and isn’t that what God is?”

Key South African HIV∫AIDS critic Sam Mhlongo dies

October 7th, 2006

Professor Sam Mhlongo, MD, one of the most stalwart practical critics of the African HIV∫AIDS pandemic story, who found his own experience of patients and their ailments differed wildly from the official version, has lost his life, according to Joan Shenton, who was phoned by Janine Roberts and reports that the doctor was killed in a road accident yesterday afternoon.

Joan Shenton interviews Mhlongo

The news has stunned all who knew him. Charles Geshekter has spoken for many dissidents and others in writing that “Sam was a consummate professional, a dear and wonderful friend, a devoted husband and a role model for schoilars, teachers, physicians, and critical thnkers around the world. South Africa and the world has lost a courageous lion of a leader.”

Professor Sam Mhlongo, M.D., returned to South Africa in 1998 after spending 36 years in exile in England during apartheid. He earned his medical degree from the University of London and practiced there for 30 years specialising in cardiology. During that time he was president chairing the Cross Medical School in London and was director of ‘African History and Current Affairs’.

After returning to South Africa he was appointed Head of the Department of Family Medicine and Primary Health Care at the Medical University of Southern Africa, now called the University of Limpopo, MEDUNSA Campus. He founded the Pfunanani Health Research Trust South Africa in 2001.

He has authored and co-authored numerous books and articles on a broad range of subjects, most notably “Forced removal of the Mamatola tribe” in 1967, ”Workers Strikes in South Africa” 1973, “Social classes in South Africa 1975”, “Atenolol post myocardial infarction”, ” Handbook of family practice” in 2000.

He has been medical science editor of African Reclamation Forum since 1999. He was a member of the Royal College of Physicians of the African Caribbean Medical Association and he was its secretary from 1994 to 1998. He is a member of the Royal College of General Practitioners UK and member of the Presidential AIDS panel of South Africa.

UPDATE: The Silkwood syndrome

Although there is no evidence yet that Mhlongo’s death was anything but a traffic accident on the way to work in Johannesburg from his home, if there was foul play (as his fellow HIV∫AIDS critics now inevitably wonder) it would be part of a trend world wide which has seen journalists in particular eliminated by professional killings.

The latest is the death on Putin’s birthday, Saturday (Oct 7) of Anna Politkovskaya, 48, severe critic of Putin (”a cynical liar” who condones torture of schoolboys in the Czechen war, she reported) and the 13th journalist killed in Putin’s reign (and the 100th to die since Glasnost in 1986), with Putin a suspect, Gorbachev calling it an outrage, and Bush calling Putin to ask questions. Meanwhile there are revelations on the BBC that suggest US Army troops deliberately fired at the ITN correspondent that died in 2003.

Anna’s funeral was held today:

The investigative reporter’s body was then laid to rest under cold and rain-filled skies.

Police said about 3000 people attended.

Among them were the Norwegian, Swedish and US ambassadors, as well as a who’s who of Russian human rights activists, but there were no high-ranking government officials.

President Vladimir Putin, who has been criticised for not reacting earlier, said during a trip to Germany that her murder had been “cruel”.

However he then sought to minimise her work as “extremely insignificant”.

The New York Times Editorial today, Oct 10 Tues,

Another Killing in Moscow:

Anna Politkovskaya, gunned down over the weekend in Moscow, was the 13th Russian journalist killed since Vladimir Putin became president — and one of the bravest. We may never know who killed her because politically motivated crimes have a way of never being solved in Mr. Putin’s Russia.

There is no question about whom Ms. Politkovskaya held responsible in years of unflinching reporting from Chechnya: the Russian Army and Mr. Putin himself. When he finally got around to acknowledging her death yesterday it was in a cold-blooded statement that the authorities “will take every step to investigate objectively the tragic death of the journalist Politkovskaya.”

Ms. Politkovskaya was 48, the mother of two grown children. She lived alone, in part because of the dangers of her job. On Saturday, she was about to deliver a major report to her newspaper about torture in Chechnya when a killer ambushed her and fired four shots from a silenced Makarov pistol, one in her heart and three in her head.

Police investigators seized all her research materials from her home and her office at Novaya Gazeta, one of the few independent newspapers still functioning in Moscow. We hope they lead to arrests, and not a cover-up. It is hard to be optimistic.

The murder of Ms. Politkovskaya — like the murder last month of Andrei Kozlov, the deputy chairman of the Russian Central Bank who was trying to reform the banking system — had the stench of a political assassination. It would be hard to imagine that Mr. Putin’s Kremlin, swollen with oil riches and power, could not find those who ordered her murder or so many others.

It is also hard to fathom why a president with Mr. Putin’s hunger for respect would allow his country to sink so steadily in the world’s esteem. Yet the former K.G.B. officer has presided over a systematic degrading of Russians’ freedoms.

According to the Committee to Protect Journalists, Russia has been the third deadliest country for journalists over the past 15 years, after Iraq and Algeria. Despite the active hostility of the state, and the clear and ever-present danger, reformers have continued to speak up. Ms. Politkovskaya believed, as did Mr. Kozlov and many others, that Russia could become a freer country. We hope that her terrible death will rally those who share her faith.

The news report in the Times, Journalist Critical of Chechen War Is Shot Dead:

The New York Times

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October 8, 2006

Journalist Critical of Chechen War Is Shot Dead

By C. J. CHIVERS

MOSCOW, Oct. 7 — Anna Politkovskaya, the veteran Russian journalist and author who made her name as a searing critic of the Kremlin and its policies in Chechnya, was found dead on Saturday in her apartment building, shot in the head with a pistol, the authorities and her colleagues said.

Ms. Politkovskaya, 48, was a journalist with few equals in Russia. She was a special correspondent for the Novaya Gazeta newspaper and had become one of the country’s most prominent human rights advocates.

In recent years, as the Russian news media faced intensifying pressure under the administration of President Vladimir V. Putin, she maintained her outspoken stance. And she became an international figure who often spoke abroad about a war she called “state versus group terrorism.”

She was a strident critic of Mr. Putin, whom she accused of stifling civil society and allowing a climate of official corruption and brutality.

She was found dead by a neighbor shortly after 5 p.m. A Makarov 9-millimeter pistol had been dropped at her side, the signature of a contract killing, Vitaly Yaroshevsky, the deputy editor of Novaya Gazeta, said in a telephone interview.

“We are certain that this is the horrible outcome of her journalistic activity,” he said. “No other versions are assumed.”

In Washington, the State Department spokesman, Sean McCormack, said the United States “urges the Russian government to conduct an immediate and thorough investigation in order to find, prosecute and bring to justice all those responsible for this heinous murder.”

The former Soviet president Mikhail S. Gorbachev, a shareholder of the newspaper where Ms. Politkovskaya worked, called her killing “a savage crime.”

“It is a blow to the entire democratic, independent press,” he told the Interfax news agency. “It is a grave crime against the country, against all of us.”

Accounts about where she died conflicted, with some law enforcement authorities saying she was found inside the entrance of her apartment building and others saying she was in the elevator.

The police said a security video camera had recorded the image of her presumed killer: a tall young man in dark clothes and a black baseball cap. They said a search for him had begun.

Ms. Politkovskaya, who had two adult children, had worked for Novaya Gazeta since 1999, and covered the second Chechen war and the terrorist siege of a Moscow theater in 2002. One of her books, “A Small Corner of Hell: Dispatches from Chechnya,” recorded her impressions of the war’s unrelenting and often macabre cruelty, and the manifest corruption of many of its participants.

She wrote of torture, mass executions, kidnappings to gain ransom and to eliminate rebel suspects, and the sale by Russian soldiers of Chechen corpses to their families for proper Islamic burial. Her writing cemented her place as one of the war’s most vocal domestic critics.

“The army and police, nearly 100,000 strong, wander around Chechnya in a state of complete moral decay,” she wrote. “And what response could one expect but more terrorism, and the recruitment of new resistance fighters?”

Since the collapse of the Soviet Union, Russia has been one of the world’s more difficult and dangerous countries for journalists. The climate has continued in recent years; at least 12 journalists have been killed in Russia in contract-style murders since 2000, according to the Committee to Protect Journalists.

None has been solved, including the contract killing in 2004 of Paul Klebnikov, the American editor of Forbes magazine’s Russian-language edition.

Ms. Politkovskaya had received death threats in the past, and at least once had left the country fearing for her safety. In 2004 she claimed to have been poisoned while en route on an airplane to cover the public school siege in Beslan; she passed out on the flight but survived. Mr. Yaroshevsky also said that Novaya Gazeta had briefly placed her under protective guard a few years ago.

But as prosecutors opened an investigation into what they called premeditated murder, her colleagues expressed astonishment that she had been killed in such a fashion, saying her public stature had seemed to lend her an aura of invincibility.

“She was doing such risky things for such a long time that it seemed she had transcended the danger,” said Tanya Lokshina, chairwoman of Center Demos, a Moscow-based human rights organization. “I am ashamed to say it, but we all felt she was next to a monument, and that she was an icon.”

Ms. Lokshina said she had been with Ms. Politkovskaya two weeks ago in Stockholm, and that nothing seemed out of order. “She never spoke about any current threats,” she said. “Everything seemed quite normal. She seemed happy and never referred to anything suspicious.”

Mr. Yaroshevsky said that Ms. Politkovskaya had been at work on Saturday finishing an article for the Monday paper about torturers in the government of Ramzan A. Kadyrov, the pro-Kremlin premier of Chechnya. He said the story included evidence and pictures.

In an interview in April with The New York Times, Ms. Politkovskaya said she had evidence of torture in Chechnya by Mr. Kadyrov’s police and other gunmen, including at least one witness who had been tortured by Mr. Kadyrov himself. Mr. Kadyrov has always vigorously denied such allegations.

Mr. Yaroshevsky said there were no immediate theories about who might be behind her killing, and noted that it might be convenient for an enemy of Mr. Kadyrov to kill Ms. Politkovskaya in order to blacken the Chechen premier’s name.

The paper had been expecting her to file the article on Saturday night, he said, and she had apparently been killed after she left her apartment for a trip to a nearby store. The RTR television station reported that investigators believed that she had been followed throughout the day.

Tina at the Times anoints DDT, Arata Kochi

October 5th, 2006


WHO malarial chief is dynamo, brings DDT spray back

Conservatives given credit, too. Million lives a year will be saved

Will AIDS elite also claim credit at their trial?

Having written in support of bringing back DDT to save the children of the poor world (Times on malaria: the solution is to deliver expensive drugs), we are gratified to see support today (Oct 5 Thu) in the Times for the new Bush-WHO move to bring back DDT spraying.

The Editorial Observer in the Times today is Tina Rosenberg, a prize winner enlightened on every global issue with the unfortunate exception of HIV?AIDS, writing a remarkable endorsement of the revival of DDT spraying in poor countries (indoors only) to combat malaria:

This is excellent news for the humans in Africa. DDT both repels mosquitoes and kills them. It is the cheapest, longest lasting and most effective insecticide, and it will not threaten the ecosystem. Unlike in the past, DDT will now be sprayed inside houses once or twice a year in minute amounts.

Along the way in The Revival of a Notorious Solution to a Notorious Scourge she makes the following points: more than a million die each year from the dread disease, Arata Kochi (pic), the new WHO malaria chief, is the dynamo at the center of the change, the US recently decided to pay for DDT spraying after years of selfish hostility to it by Western countries on exaggerated environmental grounds, nets haven’t worked because they weren’t free, and cheap medicine doesn’t work anymore because the disease is resistant to it.

Bald eagle eggs weighed more than babies

The most egregious aspect of the whole saga has been the elitist attitude of the US and Europe, which showed through when Rachel Carson’s “Silent Spring” turned extremism against DDT into pc environmentalism, after which the fact that DDT had proved stunningly effective at wiping out malaria here and round the world didn’t count any more against bald eagle eggs in the political calculation of William Ruckleshaus.

DDT was the most important insecticide in the eradication of malaria in the United States, and in malaria control in southern Europe, Asia and Latin America. With DDT, malaria cases in Sri Lanka, then called Ceylon, dropped from 2.8 million in 1946 to 17 in 1963.

But Rachel Carson’s 1962 book “Silent Spring” documented how DDT, sprayed over crops and over cities, built up in the ecosystem, killing birds and fish. William Ruckleshaus, the first head of the Environmental Protection Agency, banned DDT in 1972 for all but emergencies.

Tina slips in an apology from the aged Ruckleshaus in 2004, which seems as patronizing as ever:

This was the right decision — for the United States. Malaria was no longer an issue, and Washington needed to ensure that it would not be used on crops. But the decision had deadly consequences overseas. “If I were a decision maker in Sri Lanka, where the benefits from use outweigh the risks, I would decide differently,” Mr. Ruckleshaus told me in 2004. “It’s not up to us to balance risks and benefits for other people.”

Yes, except that Africa’s malaria programs are financed by donors and vetted by the world’s health establishment, which is dominated and financed by the United States and Europe, where DDT is also banned. People in rich countries felt it would be perceived as hypocritical to push a product in poor countries that they had banned at home. Even malariologists who knew DDT could be used safely dared not recommend it.

DDT wasn’t pc, so experts and conservatives arguing for it were brushed aside, and a million children a year died. A sad story, with some of the main elements of the HIV?AIDS debacle in it – pc politics trumping reality, experts brushed aside, the right judgement stained by coming from conservatives, illness and death weighing little in the balance.

Interestingly, the Time’s non partisan editorial credit goes to two conservatives in the Senate for the US funding breakthrough:

Conservatives in the Senate, led by Tom Coburn and Sam Brownback, have forced a revolution in Washington’s malaria programs. America now promotes effective malaria drugs, gives away bednets, and has brought back house spraying — including with DDT.

The AIDS pandemic’s angelic side

Ms Rosenberg even credits one more big factor for the renewed interest in the disease – the AIDS pandemic.

The AIDS pandemic has raised interest in third-world disease, and malaria financing has more than doubled in the last three years. African countries are also learning from South Africa, which doesn’t have to depend on donors. Since 2000, South Africa has been successfully beating malaria using the new medicines and house spraying with DDT

So the independence of South Africa from the need to wait upon Western donors allowed it to go ahead and save its children’s lives regardless of Western selfishness and wrong opinion. Well, well. What does that say to President Mbeki about the virtues of maintaining his own counsel in AIDS, one wonders?

Anyhow, AIDS panic has led to increased attention and money for malaria, saving more lives every year, potentially, than have been lost in the West to AIDS so far. So AIDS has in one way been a blessing.

So is AIDS a good thing after all?

The moral quandary for those who disapprove of a paradigm which has sent hundreds of thousands to their sickbeds and needless deaths is this. If AIDS has inadvertently helped to save the lives of a million children a year, is it all worth it in the scheme of things?

Can Anthony Fauci, Robert Gallo, Mark Wainberg, Robin Weiss, John Maddox, David Ho, John Moore and David Baltimore plead for leniency on this basis, when they enter their pleas as defendants in the upcoming Nuremburg Trials II of recalcitrant AIDS officials suggested by Larry Kramer, which when Kramer finally faces up to what is really going on we expect will be more properly be directed against those who have stood in the way of review of the evidently deadly paradigm, now exposed in both the highest level theoretical reviews and in the recent studies and reviews of the mainstream literature as inexplicable and rationally unsustainable in its key premises?

After all, what’s a few hundred thousand dead and a few million mismedicated compared with 44 million dead Africans, mostly babies? Surely the color of their skins cannot weigh in this balance?

Stupidity as a viable defense

But of course, the stalwarts of the HIV?AIDS paradigm guard can always plead stupidity. No one can possibly prove that any of these people had any idea that their favorite paradigm might really be wrong after all, can they? Which of them is demonstrably bright enough for such a charge to stick? Even CalTech president emeritus and Nobel prize winner David Baltimore made such an fool of himself in the Baltimore Affair trying to repress Margot O’Toole that he lost the Presidency of Rockefeller, so even he might have a good chance of copping the same plea in AIDS – except for the fact that he set a precedent for trying to repress the truth, which will be precisely the charge in the new Nuremburg Trial.

Arata Kochi, troublemaker

Of course, stupidity is not a word which is voiced much in genteel high level circles in government or science, however often it is thought.

Frankness on that front is however one of the charms of the new malarial chief at the WHO. Arata Kochi refreshingly admitted calling his new staff at the WHO that very word at times, after the previous chief was kicked out. Talking to the Times last month, Kochi made it pretty clear what he thought of the previous occupant too (W.H.O. Supports Wider Use of DDT vs. Malaria):

Dr. Kochi’s new policies and abrasive style have stirred the small world of malaria experts. Dr. Allan Schapira, a senior member of the W.H.O. malaria team who most recently oversaw its approach to insecticide spraying, resigned last week.

Reached Thursday on his cellphone, Dr. Schapira declined to comment on his reasons, except to say that they were professional. He did not return messages left Friday.

His successor, Pierre Guillet, a medical entomologist, said Dr. Schapira quit because he was uncomfortable with the new approach on insecticide spraying.

There are fierce debates among experts over when it is best to use indoor spraying or mosquito nets impregnated with insecticides that last up to five years, though most agree that both spraying and nets are important tools.

Dr. Kochi said in an interview that half the professional staff of the W.H.O.’s malaria program has left “one way or the other” since he took over in October. He described Dr. Schapira as the “main brain” behind the past approach.

“He was professionally insulted by me,” Dr. Kochi said.

In answer to a question, Dr. Kochi acknowledged that he had indeed told members of the staff in meetings that they were stupid. “They are very inward looking, and they do not communicate outside the malaria field,” he said. “It’s ridiculous.”

The Times’ Celia Dugger wrote that amusing report, which made Kochi sound a little over the top. But whatever works, works. He has helped to transform WHO and US policy and saved the lives of millions, it appears. We nominate this man for the post of chief advisor to Bill Gates and Bill Clinton on global disease matters, and for the Secretaryship of the UN when it comes up.

Few people deserve personal credit for saving a million lives a year. Maybe he’ll get the Nobel Peace Prize.

If so, this will encourage troublemakers everywhere, and truth may break out all over, even in HIV?AIDS.

W.H.O. Supports Wider Use of DDT vs. Malaria

The New York Times

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September 16, 2006

W.H.O. Supports Wider Use of DDT vs. Malaria

By CELIA W. DUGGER

WASHINGTON, Sept. 15 — The World Health Organization on Friday forcefully endorsed wider use of the insecticide DDT across Africa to exterminate and repel the mosquitoes that cause malaria. The disease kills more than a million people a year, 800,000 of them young children in Africa.

Dr. Arata Kochi, who leads the group’s global malaria program, unequivocally declared at a news conference on Friday that DDT was the most effective insecticide against malaria and that it posed no health risk when sprayed in small amounts on the inner walls of people’s homes. Expanding its use is essential to reviving the flagging international campaign to control the disease, he said.

Dr. Kochi has powerful allies on DDT and, more broadly, on using insecticide sprays, in Congress and the Bush administration — an odd bedfellows coalition for an agency of the United Nations, which has often been at odds with the White House.

At the news conference, Adm. R. Timothy Ziemer, who leads President Bush’s $1.2 billion malaria undertaking, stood at Dr. Kochi’s side and described spraying with insecticides as a tool “that must be deployed as robustly and strategically as possible.”

The health organization’s news release quoted Senator Tom Coburn, Republican of Oklahoma.

“Finally, with the W.H.O.’s unambiguous leadership on the issue, we can put to rest the junk science and myths that have provided aid and comfort to the real enemy — mosquitoes,” said the senator, a medical doctor.

Dr. Kochi said the most substantive change in the W.H.O.’s guidelines on the use of insecticides would extend the reach of the strategy. Until now, the agency had recommended indoor spraying of insecticides in areas of seasonal or episodic transmission of malaria, but it now also advocates it where continuous, intense transmission of the disease causes the most deaths.

Dr. Kochi’s new policies and abrasive style have stirred the small world of malaria experts. Dr. Allan Schapira, a senior member of the W.H.O. malaria team who most recently oversaw its approach to insecticide spraying, resigned last week.

Reached Thursday on his cellphone, Dr. Schapira declined to comment on his reasons, except to say that they were professional. He did not return messages left Friday.

His successor, Pierre Guillet, a medical entomologist, said Dr. Schapira quit because he was uncomfortable with the new approach on insecticide spraying.

There are fierce debates among experts over when it is best to use indoor spraying or mosquito nets impregnated with insecticides that last up to five years, though most agree that both spraying and nets are important tools.

Dr. Kochi said in an interview that half the professional staff of the W.H.O.’s malaria program has left “one way or the other” since he took over in October. He described Dr. Schapira as the “main brain” behind the past approach.

“He was professionally insulted by me,” Dr. Kochi said.

In answer to a question, Dr. Kochi acknowledged that he had indeed told members of the staff in meetings that they were stupid. “They are very inward looking, and they do not communicate outside the malaria field,” he said. “It’s ridiculous.”

Dr. Kochi earlier headed the W.H.O.’s tuberculosis campaign until he was forced out after his blunt manner alienated important partner organizations.

He has brought the same in-your-face approach to malaria. In January, he demanded that 18 drug companies — all named — stop selling some forms of a new malaria drug he believed could speed up drug resistance. If they did not comply, he threatened to try to disrupt sales of their other medicines.

In April, he accused the Global Fund to Fight AIDS, Tuberculosis and Malaria, through which rich countries finance health campaigns, of ignoring W.H.O. rules that forbid treating malaria with herbal-based therapy alone — a charge that Dr. Bernard Nahlen, a senior adviser at the Global Fund, called “outlandish” on Friday.

There are now 17 African countries using at least some indoor spraying of insecticides to combat malaria. Only 10 of them use DDT — Eritrea, Madagascar, Ethiopia, Swaziland, South Africa, Mauritius, Mozambique, Zimbabwe, Namibia and Zambia — the W.H.O. said. Too many countries in Africa have shied away from DDT, Dr. Kochi said, because of the nasty environmental reputation it earned in an earlier era when it was widely sprayed on crops — dangers that do not apply when spraying small amounts indoors.

DDT has carried a special stigma since the publication in 1962 of Rachel Carson’s “Silent Spring,” which helped set off the environmental movement in America by documenting how mass spraying of DDT entered the food chain, causing cancer and genetic damage and threatening to wipe out some bird species, including bald eagles.

The nonprofit group, Beyond Pesticides, distributed news releases on Friday opposing the W.H.O.’s new policy, saying a dependence on pesticides like DDT “causes greater long-tem problems than those that are being addressed in the short-term.”

Dr. Kochi said some African countries had also been reluctant to use DDT because of fears that European countries would block food exports if crops were tainted by even minuscule amounts of DDT. In an interview, he called on leaders of the European Union to publicly encourage African countries to use DDT against malaria. Uganda, for one, has not used it because of what Dr. Kochi called “a bureaucratic standoff between the ministry of health and the ministry that oversees trade.”

A spokesman for the European Union, Alain Bloedt, said Friday that it was too late in the afternoon to get a reply.

Dr. Kochi said he himself did not worry about whether he would lose his job if he took on too many influential players. Success will require many difficult changes, he said. “I don’t want to fail.”

The Revival of a Notorious Solution to a Notorious Scourge

The New York Times

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October 5, 2006

Editorial Observer

The Revival of a Notorious Solution to a Notorious Scourge

By TINA ROSENBERG

Of all the wars in Africa, the most deadly is between humans and mosquitoes. More than a million Africans die of malaria every year, the vast majority of them small children. Malaria shrinks the economies of countries where it is endemic by 20 percent over 15 years. One reason the mosquitoes are winning is that the world had essentially discarded its single most effective weapon, DDT.

But Washington recently resumed financing the use of DDT overseas, and the dynamic new malaria chief of the World Health Organization, Arata Kochi, has said that the W.H.O., too, endorses widespread indoor house spraying with DDT.

This is excellent news for the humans in Africa. DDT both repels mosquitoes and kills them. It is the cheapest, longest lasting and most effective insecticide, and it will not threaten the ecosystem. Unlike in the past, DDT will now be sprayed inside houses once or twice a year in minute amounts.

DDT was the most important insecticide in the eradication of malaria in the United States, and in malaria control in southern Europe, Asia and Latin America. With DDT, malaria cases in Sri Lanka, then called Ceylon, dropped from 2.8 million in 1946 to 17 in 1963.

But Rachel Carson’s 1962 book “Silent Spring” documented how DDT, sprayed over crops and over cities, built up in the ecosystem, killing birds and fish. William Ruckleshaus, the first head of the Environmental Protection Agency, banned DDT in 1972 for all but emergencies.

This was the right decision — for the United States. Malaria was no longer an issue, and Washington needed to ensure that it would not be used on crops. But the decision had deadly consequences overseas. “If I were a decision maker in Sri Lanka, where the benefits from use outweigh the risks, I would decide differently,” Mr. Ruckleshaus told me in 2004. “It’s not up to us to balance risks and benefits for other people.”

Yes, except that Africa’s malaria programs are financed by donors and vetted by the world’s health establishment, which is dominated and financed by the United States and Europe, where DDT is also banned. People in rich countries felt it would be perceived as hypocritical to push a product in poor countries that they had banned at home. Even malariologists who knew DDT could be used safely dared not recommend it.

The United States, which used DDT irresponsibly to wipe out malaria, ended up blocking much poorer and sicker countries from using it responsibly. Under American pressure, several Latin American countries that had controlled malaria stopped using DDT — and in most of them, malaria cases soared.

The other reason for DDT’s demise was donor tightfistedness. DDT has to be sprayed inside houses, an activity that needs to be carried out by governments. In most African countries, this means donors must pay. They balked, and insecticide-treated bednets became bureaucrats’ preferred solution. Donors liked the program because it was cheap and sustainable, as consumers would buy the nets — often at subsidized prices. But it has failed. The nets work — but even at $5, few can buy them. The most recent data show that only 3 percent of African children sleep under treated nets.

The eradication of malaria in rich countries turned out to be the worst thing that happened for people with malaria in poor countries. Malaria lost its constituency, and the money dried up. Throughout Africa, until recently, countries were using chloroquine to cure malaria, a medicine that cost pennies, and so could be bought by rural families. But mosquitoes had become resistant to it. And donors were unwilling to spend the money for effective medicines.

But this is changing. The AIDS pandemic has raised interest in third-world disease, and malaria financing has more than doubled in the last three years. African countries are also learning from South Africa, which doesn’t have to depend on donors. Since 2000, South Africa has been successfully beating malaria using the new medicines and house spraying with DDT.

Conservatives in the Senate, led by Tom Coburn and Sam Brownback, have forced a revolution in Washington’s malaria programs. America now promotes effective malaria drugs, gives away bednets, and has brought back house spraying — including with DDT.

Malaria soared because the forces allied against it quit the battlefield. Now the humans are back.

In Europe, fish oil after heart attacks – but not here

October 3rd, 2006


Times reporter in Rome discovers amazing difference in treatment

Classic example of how US system defeats natural antidotes

Real solution is obvious – but far away

The seventh and eighth most searched keywords at the Times today were “health” and “science”, one ahead of “bush”. And we bet it is because of the article on taking fish oil after heart attacks, which is the second most emailed article.

What Elizabeth Rosenthal in Rome has found out will confirm the worst fears of those who suspect the drug companies and the FDA are somehow in cahoots against the welfare of Americans, refusing to give us what the Europeans in their more ancient wisdom hand out freely to their sick and diseased – in this case a key nutritional supplement which protects patients from dying after they have a heart attack.

Her article is polite and balanced in the Times manner so one has to read it closely to find out exactly what is going on. But it seems according to In Europe It’s Fish Oil After Heart Attacks, but Not in U.S. that the big Italian study ten years ago showed a sizeable indication that purified fish oil, or omega-3 fatty acids, can reduce deaths over three years by 20 per cent, and sudden deaths by forty per cent, if you dose heart attack patients within 24 hours after the event.

But there was a minor imperfection in the methodology – the study control group was untreated, rather than given a placebo – so the FDA will not accept the study’s impressive results, even though regulators in Spain, France, and Britain approved the prescription fish oil version, brand name Omacor, by 2004, and in Italy, according to the chief of cardiology at the Rome hospital Rosenthal quotes, every patient who survives a heart attack goes home with a prescription, and it is “considered tantamount to malpractice in Italy to omit the drug.”

Plenty of authoritative sources in the US support the practice too, Rosenthal finds, including a study in the Journal of the American Board of Family Medicine last month which said it was “important advice” to give patients.

But in the US patients are not given omega-3’s, nor are they offered information on it on the Omacor manufacturer’s Web site, which when it finds out you are a US citizen steers you past the information to a page where heart attacks are not mentioned! Instead, cardiologists and hospitals routinely offer more expensive and invasive treatments, in the form of pills and implanted defibrillators:

But in the United States, heart attack victims are not generally given omega-3 fatty acids, even as they are routinely offered more expensive and invasive treatments, like pills to lower cholesterol or implantable defibrillators. Prescription fish oil, sold under the brand name Omacor, is not even approved by the Food and Drug Administration for use in heart patients.

“Most cardiologists here are not giving omega-3’s even though the data supports it — there’s a real disconnect,” said Dr. Terry Jacobson, a preventive cardiologist at Emory University in Atlanta. “They have been very slow to incorporate the therapy.”

Whose fault is it?

So is this the fault of the drug companies, whose ads and salesmen steer the US medical fraternity to the drugs and tools they sell, and who in the absence of FDA approval for Omacor cannot even mention the European solution? Hardly. The lack of FDA approval means they can make no money out of it, without a hugely expensive clinical trial.

Because prescription fish oil is not licensed to prevent heart disease in the United States, drug companies may not legally promote it for that purpose at conferences, in doctors’ offices, to patients or even on the Internet.

“If people paid more attention to guidelines, more people would be on the drug,” Dr. Jacobson said. “But pharmaceutical companies can’t drive this change. The fact that it’s not licensed for this has definitely kept doctors away.”

For example, on Solvay Pharmaceutical’s Web site for Omacor, www.solvay-omacor.com, the first question a user sees is, “Are you a U.S. citizen?”

If the answer is yes, the user is sent to a page where heart attacks are not mentioned. (In the United States, Omacor is licensed only to treat the small number of people with extremely high blood triglyceride levels.)

So community doctors do not learn how to use the drug. Lack of F.D.A. approval also means that insurers will not pay for treatment with Omacor. Approval from the agency for the use of the drug in heart disease is not expected soon.

A study published last month in The Journal of the American Board of Family Medicine found that only 17 percent of family doctors were likely to prescribe fish oil to their patients, including patients who had suffered a heart attack. There was a great need, the authors concluded, to “improve awareness of this important advice.”

A lousy system, but why?

Clearly this is a lousy system in some respect or other. But what is the flaw? Maybe heart attack victims should rise up and storm the gates of the FDA and the NIH, and demand their rights. Why should they not be told about fish oil, have fish oil prescribed, see fish oil ads and read about them on the Web?

Come to think of it, why does this stuff need a precription anyway? Is pure fish oil a danger to your health in some way? The entire Mediterranean tradition says not. The Italians and the Greeks flourish on their delightful cuisine with minimal heart attacks, and as the article notes scientists have theorized as we all have that it’s the fish that do it, along with the wine.

And why does it have to be pure? According to Rosenthal,

over-the-counter preparations of fish oil have much less rigorous quality control and are often blends of the two fish oils know to be beneficial in heart disease with other less useful fatty acids.

For that reason, Dr. Jacobson of Emory gives the prescription drug, “off label,” to cardiac patients, even though the F.D.A. has not approved it for that use. “Then I know exactly what they’re getting, and there is no mercury,” he said.

So according to this the dangers of non-precription versions are “less useful fatty acids” and “mercury”. Is that a reason not to have generic fish oil available?

Still, hard to see why the company with the license for the drug in the US doesn’t seem in a hurry to go through the necessary trials in the US and market Omacor here. Could it be the cost of such trials, which involve hundreds of millions of dollars?

Marylou Rowe, a spokeswoman for Reliant Pharmaceuticals, which owns the license for the drug in the United States, said that further trials of Omacor would be needed for it to be licensed for heart attack patients in the United States. But she refused to discuss a timetable.

Why is is “ethical” to withhold fish oil and not HAART?

The whole story is a classic study of what is wrong with the health delivery system in the US. The FDA is placing a giant hurdle for an obviously beneficial natural compound to jump over before it can be part of the system, and while it is kept from being prescribed all the experts salute its benefit and even pop omega-3 pills themselves.

Rather embarrassing parallels can be seen in the world of HIV∫AIDS where it is becoming rather evident that what the top scientists know and talk about quietly among themselves is a lot more enlightened than what they release for public consumption.

For example, the aforementioned JAMA study below breaking the link between the virus and immune cell depletion which is now causing a little debate in Science and elsewhere, where the authors of the study plainly say it knocks out a basic assumption of the paradigm, but are careful to state their faith in the paradigm itself at every public opportunity to avoid getting in Dutch with Dr Fauci.

We have a friend who recently had a heart attack and was carted off to hospital for a triple by pass. Apparently we now have the duty of briefing him on the need to ask his cardiologist about omega-3 fatty acids when we see him next. Evidently the system cannot now be trusted in this simple matter.

As for the methodological weakness of the massive Italian study which brought the good news in the first place, is this really important enough for the FDA to hesitate before giving permission to cardiologists to prescribe them if they wish?

the landmark Gissi-Prevenzione trial of fish oil had methodological weaknesses: the patients treated with prescription fish oil pills were compared with untreated patients, rather than with patients given a dummy pill. This meant that, despite impressive results, the trial did not meet the F.D.A.’s standards for approval. Yet by 2004, regulators in almost all European countries, including Spain, France and Britain, had approved Omacor for use in heart attack patients.

Obviously not.

After all, if the FDA officials can see their way to forgiving the need for placebo groups in trials of the most dangerous HIV∫AIDS drugs, why is it so hard for them to forgive a slight methodological weakness in a huge trial of a familiar natural substance that the entire world agrees is good for you and rule that it would be “unethical” to withhold it from Americans after heart attacks?

The real solution is far, far away

The story highlights the basic problem with the current profit based system, where “the fundamental premise of US health care is that patients suffer from a deficiency in drugs,” as Robert Houston has wittily observed.

What is needed is for the government to finance nutritional and other approaches to combating ill health which cannot be patented and/or cannot ever be profitable enough to justify the hundreds of millions of dollars needed to finance clinical trials to win approval from the FDA (up to $900 million according to a Tufts University study).

But of course in their extreme capitalist frenzy it is unlikely that our present rulers or their party will ever recognize the fact that economics has a welfare dimension which cannot be reliably covered by the activities of profit making companies, unless government takes action in some way to provide incentives.

So for the moment we will just have to hope that the senior guilt trips of robber barons and other highly successful entrepreneurs and investors such as Bill Gates and Warren Buffett will include the idea of funding unprofitable avenues of research into alternatives to profitable drugs.

What we are saying is simple: someone should call or phone Bill Gates, Bill or Hilary Clinton, or any other parties of influence and get either government officials or rich men to fund the trials of natural alternatives so that the FDA has more to license than the latest profit making synthetic drug to come down the pipeline after trials which in HIV∫AIDS at least are notoriously corrupt and which novel chemicals are generally unpredictable in terms of side effects when mixed with numbers of other commercial drugs given the patients, as is so often the case with seniors.

In a sane system it may be that the NIH should be spending $3 billion a year on such trials, starting, for example, with selenium and its relevancy to the health of the immune system.

Under the current system the products of mother nature are effectively banned in favor of synthetic drugs, because they cannot be patented so if any company pays for expensive trials it cannot be sure of payback, since companies with competing versions will be free to come in and exploit the market without any upfront cost.

What’s even more egregious is the kind of thing that happened with AZT where the government paid for invention of the drug and the trials and then handed over the patent to Burroughs Wellcome who proceeded to jack up the price and make money killing people with high doses of this DNA chain terminator branded as Retrovir.

(In Europe It’s Fish Oil After Heart Attacks, but Not in U.S. by Elizabeth Rosenthal:

October 3, 2006

In Europe It’s Fish Oil After Heart Attacks, but Not in U.S.

By ELISABETH ROSENTHAL

ROME — Every patient in the cardiac care unit at the San Filippo Neri Hospital who survives a heart attack goes home with a prescription for purified fish oil, or omega-3 fatty acids.

“It is clearly recommended in international guidelines,” said Dr. Massimo Santini, the hospital’s chief of cardiology, who added that it would be considered tantamount to malpractice in Italy to omit the drug.

In a large number of studies, prescription fish oil has been shown to improve survival after heart attacks and to reduce fatal heart rhythms. The American College of Cardiology recently strengthened its position on the medical benefit of fish oil, although some critics say that studies have not defined the magnitude of the effect.

But in the United States, heart attack victims are not generally given omega-3 fatty acids, even as they are routinely offered more expensive and invasive treatments, like pills to lower cholesterol or implantable defibrillators. Prescription fish oil, sold under the brand name Omacor, is not even approved by the Food and Drug Administration for use in heart patients.

“Most cardiologists here are not giving omega-3’s even though the data supports it — there’s a real disconnect,” said Dr. Terry Jacobson, a preventive cardiologist at Emory University in Atlanta. “They have been very slow to incorporate the therapy.”

The fact that heart patients receive such different treatments in sophisticated hospitals around the world highlights the central role that drug companies play in disseminating medical information, experts said.

Because prescription fish oil is not licensed to prevent heart disease in the United States, drug companies may not legally promote it for that purpose at conferences, in doctors’ offices, to patients or even on the Internet.

“If people paid more attention to guidelines, more people would be on the drug,” Dr. Jacobson said. “But pharmaceutical companies can’t drive this change. The fact that it’s not licensed for this has definitely kept doctors away.”

For example, on Solvay Pharmaceutical’s Web site for Omacor, www.solvay-omacor.com, the first question a user sees is, “Are you a U.S. citizen?”

If the answer is yes, the user is sent to a page where heart attacks are not mentioned. (In the United States, Omacor is licensed only to treat the small number of people with extremely high blood triglyceride levels.)

So community doctors do not learn how to use the drug. Lack of F.D.A. approval also means that insurers will not pay for treatment with Omacor. Approval from the agency for the use of the drug in heart disease is not expected soon.

A study published last month in The Journal of the American Board of Family Medicine found that only 17 percent of family doctors were likely to prescribe fish oil to their patients, including patients who had suffered a heart attack. There was a great need, the authors concluded, to “improve awareness of this important advice.”

The fact that fish oil is also sold as a nutritional supplement has made it harder for some doctors to regard it as a powerful drug, experts said.

“Using this medicine is very popular here in Italy, I think partly because so many cardiologists in this country participated in the studies and were aware of the results,” said Dr. Maria Franzosi, a researcher at the Mario Negri Institute in Milan. “In other countries, uptake may be harder because doctors think of it as just a dietary intervention.”

In the largest study of fish oil — conducted more than a decade ago — Italian researchers from the Gissi Group (Gruppo Italiano per lo Studio della Sopravvivenza nell’Infarto), gave 11,000 patients one gram of prescription fish oil a day after heart attacks. After three years, the study found that the number of deaths was reduced by 20 percent and that the number of sudden deaths by 40 percent, compared with a control group.

Later studies have continued to yield positive results, although some scientists say there are still gaps in knowledge.

This summer, a critical review of existing research in BMJ, The British Medical Journal, “cast doubt over the size of the effect of these medications” for the general population, said Dr. Roger Harrison, an author of the paper, “but still suggested that they might benefit some people as a treatment.”

Dr. Harrison said he believed that people should generally increase their intake of omega-3 acids, best done by eating more fish.

Still, he acknowledged that it was difficult to eat foods containing a gram of omega-3 acids each day. “If you ask me do I take omega-3 supplements every day, then, embarrassingly, the answer is yes,” said Dr. Harrison, a professor at Bolton Primary Care Trust of the University of Manchester in England.

“I, too, am caught up in this hectic world where I have little time to shop and prepare the healthy foods I know I should be eating,” he said.

It seems natural for Italy to be at the forefront of the fish oil trend and home to the largest clinical trials. Scientists have long noted that Mediterranean diets are salubrious for the heart and theorized that the high content of broiled and baked fish might be partly responsible.

But the landmark Gissi-Prevenzione trial of fish oil had methodological weaknesses: the patients treated with prescription fish oil pills were compared with untreated patients, rather than with patients given a dummy pill. This meant that, despite impressive results, the trial did not meet the F.D.A.’s standards for approval. Yet by 2004, regulators in almost all European countries, including Spain, France and Britain, had approved Omacor for use in heart attack patients.

Marylou Rowe, a spokeswoman for Reliant Pharmaceuticals, which owns the license for the drug in the United States, said that further trials of Omacor would be needed for it to be licensed for heart attack patients in the United States. But she refused to discuss a timetable.

The American College of Cardiology now advises patients with coronary artery disease to increase their consumption of omega-3 acids to one gram a day, but it does not specify if this should be achieved by eating fish or by taking capsules. But over-the-counter preparations of fish oil have much less rigorous quality control and are often blends of the two fish oils know to be beneficial in heart disease with other less useful fatty acids.

For that reason, Dr. Jacobson of Emory gives the prescription drug, “off label,” to cardiac patients, even though the F.D.A. has not approved it for that use. “Then I know exactly what they’re getting, and there is no mercury,” he said.

He said he tells patients who cannot afford the prescription version that they can take the over-the-counter supplements, although there is uncertainty about the dose and they probably need three to four pills a day.

In Europe, meanwhile, research on prescription fish oil, which is now thought to act by stabilizing cell membranes, has gained momentum. The Gissi Group is conducting two huge trials using fish oil in patients with abnormal heart rhythms and in patients with heart failure.


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